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Cagrilintide

Cagrilintide

Dual-Chamber Pen

Cagrilintide Peptide Pen is available in a 10 mg strength and contains a long-acting analogue of amylin, a naturally occurring hormone involved in satiety, appetite and food-intake regulation. Clinical studies of Cagrilintide have reported substantial reductions in body weight, creating significant interest in its effects on appetite and energy balance.

Cagrilintide acts through the amylin pathway, which is involved in feelings of fullness, gastric emptying and the regulation of food intake. This provides a different research approach to weight regulation than GLP-1-based compounds.

PCP’s proprietary Dual-Chamber Technology keeps the lyophilised Cagrilintide separate from the bacteriostatic water until activation.

For laboratory research use only. Not intended for human or veterinary use.

Strength
2.890,00 CZK
2.890,00 CZK
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Product Details

The Cagrilintide Dual-Chamber Peptide Pen is supplied in a preloaded format that keeps the lyophilised Cagrilintide powder and diluent physically separated until preparation. This allows both components to remain unmixed during storage and transport.

Each pen is clearly identified and professionally packaged to support product protection, straightforward handling and reliable identification within qualified research environments.

Product highlights:

• Dual-chamber configuration with separately contained Cagrilintide powder and diluent
• Supplied unmixed until laboratory preparation
• Available in a 10 mg strength
• Provides 100 dial units in total
• One complete dual-chamber cartridge per pen
• Five 32G × 4 mm needle tips included
• Protective packaging for storage and transport
• Certificate of Analysis (COA) available

Technical specifications, dial-unit information, storage requirements and handling guidance are provided to support product identification and responsible laboratory use.

Technical Specifications
Intended Use
For laboratory research use only. Not for human or veterinary use.
Shipping Condition
Securely packaged for transport with tracked delivery.
Storage Temperature
Unopened/unmixed: store refrigerated at 2–8°C. After mixing: store refrigerated at 2–8°C. Do not freeze. Protect from light.
Presentation
One pre-filled double-chamber research pen containing unmixed components, supplied with three 32G × 4 mm needle tips
Form
Lyophilized peptide powder and diluent maintained in separate chambers
Compound Identity
Compound: Cagrilintide

Compound type: Synthetic, acylated long-acting analogue of human amylin

Research classification: Amylin- and calcitonin-receptor agonist investigated in connection with metabolic signalling, gastric-motility processes, nutrient-associated communication, pancreatic hormone responses and energy-homeostasis pathways

Refer to the applicable product and batch documentation for verified analytical and chemical identity information.
Pen Specifications

Each pen contains a 1 mL cartridge. The amount represented by one dial unit depends on the selected pen strength. The tables below show the corresponding values for each available strength.

Pen Specifications
Pen strength Cartridge 1 dial unit
10 mg 1 mL 0.1 mg

Dial-Unit Conversion Reference

The table shows the amount represented by each listed dial setting for the available pen strengths.

Dial-unit reference by pen strength
Dial units 10 mg
1 0.1 mg
4 0.4 mg
5 0.5 mg
10 1.0 mg
20 2.0 mg
40 4.0 mg

Research-use information: Dial-unit values are provided solely for product identification, quantitative laboratory planning and documentation. They are not administration or clinical dosing instructions.

Storage & Handling

Recommended storage: Unopened/unmixed: store refrigerated at 2–8°C. After mixing: store refrigerated at 2–8°C. Do not freeze. Protect from light.

Protect the product from light and moisture and minimise unnecessary exposure to room temperature.

Complete storage and handling guidance is provided in the product information section below.

Research Use Only

All Pencell Peptide (PCP) products are supplied exclusively for laboratory research use by qualified professionals. They are not intended for human or veterinary use, consumption, personal use, medical, therapeutic, or diagnostic applications. Customers are responsible for lawful purchase, storage, handling, use, and disposal in accordance with applicable regulations and approved laboratory procedures.

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Protected by Design

Peptide and diluent remain separate until preparation

≥98% Purity

HPLC verified for research grade quality

Controlled Conditions

Prepared with a focus on consistency and research quality

Certificate of Analysis

Provided with Every Lot

Scientific Overview

Scientific Background

Cagrilintide is a synthetic, long-acting analogue of human amylin, a naturally occurring 37-amino-acid hormone involved in communication between the pancreas, digestive system and brain. Amylin plays an important role in satiety, food intake, gastric emptying and energy balance.

Cagrilintide contains targeted structural modifications and a lipid side chain designed to improve stability, reduce peptide aggregation and extend its activity. This makes it a useful example of how peptide engineering can preserve the function of a natural signalling molecule while substantially changing its duration and molecular behaviour.

Its activity is primarily associated with amylin receptors, which are formed from the calcitonin receptor together with receptor activity-modifying proteins (RAMPs). Through these receptor systems, researchers can investigate signalling involved in appetite regulation, feelings of fullness, gastric motility and metabolic control.

Cagrilintide’s prolonged-action profile also allows comparison with natural amylin and other metabolic peptides, helping researchers understand how receptor activity, peptide acylation and molecular stability relate to the effects observed in preclinical and clinical studies.

This information is provided as general scientific background for laboratory research purposes.
Research Context

Research Applications

Areas examined within controlled laboratory research.

Cagrilintide is a synthetic, long-acting analogue of human amylin, a 37-amino-acid hormone involved in communication between the pancreas, digestive system and brain. Amylin plays an important role in satiety, food intake, gastric emptying and energy balance.

Cagrilintide’s modified structure extends its activity, allowing researchers to investigate how sustained amylin signalling influences appetite, feelings of fullness, food intake and body-weight regulation. This is particularly interesting because it targets the amylin pathway, offering a different approach to metabolic research than GLP-1-based compounds.

Current areas of scientific investigation include:

  1. Amylin-receptor signalling (Cagrilintide)

    Research examining how Cagrilintide interacts with different amylin-receptor subtypes and influences downstream intracellular signalling pathways.

  2. Calcitonin-receptor activity (Cagrilintide)

    Studies exploring Cagrilintide’s activity at the calcitonin receptor and its relationship with signalling across the wider amylin–calcitonin receptor family.

  3. Pancreatic hormone communication (Cagrilintide)

    Research examining interactions between amylin-associated signalling and experimental models involving insulin, glucagon and nutrient-responsive pancreatic pathways.

  4. Peptide acylation and stability (Cagrilintide)

    Studies evaluating how Cagrilintide’s structural modifications and lipid side chain influence molecular stability, aggregation behaviour and sustained receptor engagement.

  5. Comparative metabolic signalling (Cagrilintide)

    Comparative investigation of Cagrilintide alongside naturally occurring amylin, shorter-acting amylin analogues and other metabolically active peptides.

Studies of Cagrilintide have explored how prolonged activation of amylin receptors influences appetite regulation, satiety and energy balance. Research has focused particularly on signalling pathways involved in the regulation of food intake and their relationship with broader metabolic processes.

Researchers have also investigated Cagrilintide in relation to body-weight regulation, gastric emptying and glucose metabolism, helping to clarify the role of amylin signalling in metabolic control.

Further research continues to examine how Cagrilintide’s modified structure and extended duration of action influence receptor activity, metabolic signalling and energy homeostasis.

For laboratory research purposes only. Not intended for human or veterinary use.

Important Notice Research Use Only View complete notice

All products supplied by Pencell Peptide (PCP), including its dual-chamber peptide research pens, are intended strictly for laboratory research purposes only.

These products are not intended for human or animal consumption, medical or veterinary use, therapeutic applications, diagnostic procedures or any other clinical purpose.

Customers are responsible for complying with all applicable laws, regulations and institutional requirements governing the purchase, possession, handling, storage and use of peptide research materials.

Read the complete Research Use Only notice .