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GHK-Cu

GHK-Cu

Dual-Chamber Pen

GHK-Cu Peptide Pen contains 50 mg of GHK-Cu, a naturally occurring copper-binding tripeptide that has attracted research interest for its involvement in skin and tissue repair, collagen production, wound healing and cellular regeneration.

GHK-Cu binds copper ions and helps make copper available to biological processes involved in tissue remodelling and cellular signalling. Research has particularly explored its effects on fibroblasts and the extracellular matrix, including pathways associated with collagen and other structural components of tissue.

PCP’s proprietary Dual-Chamber Technology keeps the lyophilised GHK-Cu separate from the bacteriostatic water until activation, providing a practical, self-contained format for laboratory preparation.

For laboratory research use only. Not intended for human or veterinary use.

Strength
1.090,00 CZK
1.090,00 CZK
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Product Details

The GHK-Cu Dual-Chamber Research Pen is supplied as a complete, preloaded system containing lyophilised GHK-Cu and sterile diluent in two physically separated chambers. The components remain unmixed throughout storage and transport and are combined only when the pen is activated for laboratory preparation.

The 50 mg strength is clearly identified and presented in protective packaging for straightforward product selection, handling and storage within qualified research environments.

Product highlights:

• Proprietary dual-chamber configuration
• Lyophilised GHK-Cu and sterile diluent contained separately
• Components remain unmixed until activation
• Available in 50 mg strength
• Provides 100 dial units in total
• One complete dual-chamber research pen
• Five 32G × 4 mm needle tips included
• Protective packaging for storage and transport
• Certificate of Analysis (COA) available

Technical specifications, storage conditions and handling guidance are provided separately to support accurate product identification and responsible laboratory use.

Technical Specifications
Intended Use
For laboratory research use only. Not for human or veterinary use.
Shipping Condition
Securely packaged for transport with tracked delivery.
Storage Temperature
Unopened/unmixed: store refrigerated at 2–8°C. After mixing: store refrigerated at 2–8°C. Do not freeze. Protect from light.
Presentation
One pre-filled double-chamber research pen containing unmixed components, supplied with three 32G × 4 mm needle tips
Form
Lyophilized peptide powder and diluent maintained in separate chambers
Compound Identity
Compound: GHK-Cu

Compound type: Copper-binding tripeptide complex

Research classification: Metal–peptide complex investigated in connection with copper coordination, fibroblast activity, extracellular-matrix regulation and cellular signalling

Refer to the applicable product and batch documentation for verified analytical and chemical identity information.
Pen Specifications

Each pen contains a 1 mL cartridge. The amount represented by one dial unit depends on the selected pen strength. The tables below show the corresponding values for each available strength.

Pen Specifications
Pen strength Cartridge 1 dial unit
50 mg 1 mL 0.5 mg

Dial-Unit Conversion Reference

The table shows the amount represented by each listed dial setting for the available pen strengths.

Dial-unit reference by pen strength
Dial units 50 mg
1 0.5 mg
4 2.0 mg
5 2.5 mg
10 5.0 mg
20 10.0 mg
40 20.0 mg

Research-use information: Dial-unit values are provided solely for product identification, quantitative laboratory planning and documentation. They are not administration or clinical dosing instructions.

Storage & Handling

Recommended storage: Unopened/unmixed: store refrigerated at 2–8°C. After mixing: store refrigerated at 2–8°C. Do not freeze. Protect from light.

Protect the product from light and moisture and minimise unnecessary exposure to room temperature.

Complete storage and handling guidance is provided in the product information section below.

Research Use Only

All Pencell Peptide (PCP) products are supplied exclusively for laboratory research use by qualified professionals. They are not intended for human or veterinary use, consumption, personal use, medical, therapeutic, or diagnostic applications. Customers are responsible for lawful purchase, storage, handling, use, and disposal in accordance with applicable regulations and approved laboratory procedures.

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Protected by Design

Peptide and diluent remain separate until preparation

≥98% Purity

HPLC verified for research grade quality

Controlled Conditions

Prepared with a focus on consistency and research quality

Certificate of Analysis

Provided with Every Lot

Scientific Overview

Scientific Background

GHK-Cu is a copper-binding peptide complex formed when the tripeptide glycyl-L-histidyl-L-lysine (GHK) binds a copper ion. GHK consists of just three amino acids, whose arrangement allows the peptide to coordinate copper and participate in a range of biological processes.

GHK occurs naturally in biological fluids, while its copper-bound form, GHK-Cu, is studied for the way it binds and transports copper. This is particularly interesting because copper is involved in processes including collagen formation, connective-tissue organisation and cellular signalling.

Experimental research has investigated GHK-Cu in fibroblast, dermal and other cellular models, examining its relationship with extracellular-matrix regulation, collagen-associated processes, cell migration, gene expression and oxidative-stress responses.

What makes GHK-Cu distinctive is the combination of the peptide itself and its coordinated copper ion. Researchers can therefore investigate not only its cellular activity, but also how metal binding influences peptide behaviour, tissue-remodelling pathways and cellular responses to stress and repair.

This information is provided as general scientific background for laboratory research purposes.
Research Context

Research Applications

Areas examined within controlled laboratory research.

The distinctive structure of GHK-Cu combines the three-amino-acid peptide glycyl-L-histidyl-L-lysine (GHK) with a copper ion. This ability to bind and transport copper is central to its biological activity and has made GHK-Cu an important subject of research into tissue repair, collagen production and extracellular-matrix remodelling.

Studies in cellular and tissue models have explored its effects on fibroblast activity, cell migration and gene expression, as well as pathways involved in wound repair and oxidative-stress responses. Researchers are particularly interested in how the copper-peptide complex influences processes involved in maintaining and rebuilding the extracellular matrix.

Current areas of scientific investigation include:

  1. Copper Coordination & Transport

    Investigation of GHK-Cu as a metal–peptide complex, including how the glycyl-L-histidyl-L-lysine sequence binds copper ions and participates in copper coordination and transport under controlled experimental conditions.

  2. Fibroblast and Matrix Activity

    Study of GHK-Cu-associated responses in fibroblast cultures, including cellular activity and signalling processes connected with the production, organisation and maintenance of extracellular-matrix components.

  3. Collagen Synthesis & Organisation

    Investigation of GHK-Cu in experimental models examining collagen synthesis, deposition and organisation, together with related molecular processes involved in extracellular-matrix structure.

  4. Extracellular-Matrix Regulation

    Research into the relationship between GHK-Cu and extracellular-matrix components, including glycosaminoglycan and proteoglycan expression, matrix organisation and remodelling-associated activity.

  5. Cell Migration & Repair Signalling

    Study of cellular migration and repair-associated signalling observed in dermal, fibroblast and other controlled cellular models involving GHK-Cu.

  6. Oxidative-Stress Responses

    Investigation of how GHK-Cu relates to oxidative-stress pathways, antioxidant-associated cellular responses and molecular activity under experimentally induced stress conditions.

  7. Gene Expression & Cellular Ageing

    Research into GHK-Cu-associated changes in gene expression, including molecular pathways connected with cellular senescence, tissue organisation and other age-associated biological processes.

Studies of GHK-Cu have reported a range of biological activities, particularly in experimental models of wound repair, collagen production and tissue remodelling. Research has shown effects on fibroblast activity and extracellular-matrix components, helping researchers understand how the copper-peptide complex participates in tissue organisation and repair.

Other studies have explored GHK-Cu’s influence on gene expression, cellular migration and oxidative-stress responses, suggesting that its activity extends beyond simply transporting copper. These findings have made it particularly interesting for research into how copper coordination can influence cellular signalling and regenerative processes.

Experimental methods may include copper-binding studies, fibroblast and dermal cell models, extracellular-matrix analysis and gene-expression studies, with appropriate controls and conditions established for each study.

For laboratory research purposes only. Not intended for human or veterinary use.

Important Notice Research Use Only View complete notice

All products supplied by Pencell Peptide (PCP), including its dual-chamber peptide research pens, are intended strictly for laboratory research purposes only.

These products are not intended for human or animal consumption, medical or veterinary use, therapeutic applications, diagnostic procedures or any other clinical purpose.

Customers are responsible for complying with all applicable laws, regulations and institutional requirements governing the purchase, possession, handling, storage and use of peptide research materials.

Read the complete Research Use Only notice .